Nano SiO2 catalyzed synthesis of Imidazo[1,2-a]pyridines
OPEN ACCESS
A facile microwave assisted reaction of phenacyl bromide and 2-amino pyridine is catalyzed by Nano SiO2 under solvent free conditions to give corresponding Imidazo[1,2-a]pyridines in good yields. Reactions proceed with high efficiency and good functional group tolerance. This approach provides a useful protocol for the preparation of highly substituted Imidazo[1,2-a]pyridine derivatives
nano SiO2, microwave irradiation, Imidazo[1,2-a]pyridines, phenacyl bromide
We are highly thankful to GMR Institute of Technology, Rajam for financial assistance
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